Endocrine Abstracts

Context: Acromegaly is a rare disease caused by excessive growth hormone (GH) secretion, mostly induced by pituitary adenomas. The care of pregnant women with acromegaly is challenging, in part due to existing clinical data being limited and not entirely consistent with regard to potential risks for mother and child.Objective: To retrospectively examine data on pregnancy and maternal as well as neonatal outcomes in patients with acromegaly.<p class="...

Introduction: The thyroid hormone (TH) status is routinely assessed by thyrotropin (TSH) and thyroxine (T4). Both biomarkers are mainly regulated by thyroid hormone receptor beta, whereas many peripheral organs employ the alpha receptor. Serum CD5L is a liver-derived protein under control of both TH receptor isoforms, but the data base is small [1]. An additional biomarker of TH status is needed in particular during pregnancy, where the routine biomarkers become dynamically di...